| Program I |
Protein Supplemental Therapy using Transduced Pre-adipocytes
|
 |
1. Congenital Lipid
Metabolic Disorder |
Congenital lack of lipid-metabolizing enzyme in reverse choresterol transport
leads to serious dysfunction in organs, which lower patients' QOL significantly.
In the absence of a effective treatment, gene therapy can provide great
benefits to patients. |
2. Hemophilia &
Other Orphan Diseases |
Hemophilia due to congenital lack of anticoagulant is a serious concern
in many countries worldwide. Factor VIII supplement therapy by gene therapy
can avoid frequent medications and a risk from blood products. Other orphan
diseases including lysosomal enzyme deficiency are being considered. |
| 3. Severe Diabetes |
For severe diabetics who are unable to inject insulin because of the complications
such as retinopathy, neuropathy and CVD. Continuous supplements of insulin
without a risk of infection is highly expected. |
| Program II |
Skin Ucers Treatment with Stem Cell Mobilization
|
 |
4. Intractable skin ulcers |
Cytokine treatments are already available in this field. Our drug is in
liquid formulation for external use in liquid. One of our current target
of this program is bed sores. There is the potential to be applied for
ulcers from arteriosclerotic obliterans (ASO) and diabetes. |